Symbol
Name
ID

Cdkn2b
cyclin dependent kinase inhibitor 2B
MGI:104737

Phenotype annotations related to immune system

Darker colors indicate more annotations

Human Phenotypes	Neutropenia	Leukocytosis	Leukopenia	Acute myeloid leukemia	Acute promyelocytic leukemia	Stomatitis	Lymphadenopathy	Chronic infection
Disease(s) Associated with CDKN2B	Neutropenia	Leukocytosis	Leukopenia	Acute myeloid leukemia	Acute promyelocytic leukemia	Stomatitis	Lymphadenopathy	Chronic infection
acute myeloid leukemia
acute promyelocytic leukemia

Mouse Phenotypes

spleen hyperplasia

myeloid hyperplasia

increased mature B cell number

increased monocyte cell number

abnormal lymphocyte morphology

abnormal spleen morphology

abnormal spleen marginal zone morphology

abnormal lymph node secondary follicle morphology

abnormal lymph node germinal center morphology

lymph node hyperplasia

lymphoid hyperplasia

Availability

Mouse Genotype

Cdkn2b^tm1Bbd/Cdkn2b^tm1Bbd

Cdkn2b^tm1Wff/Cdkn2b^tm1Wff
Lyz2^tm1(cre)Ifo/Lyz2⁺ (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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